FITC标记的锌指蛋白843抗体
产品名称： FITC标记的锌指蛋白843抗体
英文名称： Anti-ZNF843/FITC
产品编号： HZ-12225R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ZNF843/FITC Conjugated antibody
FITC标记的锌指蛋白843抗体
| 英文名称 | Anti-ZNF843/FITC |
| 中文名称 | FITC标记的锌指蛋白843抗体 |
| 别 名 | Zinc finger protein 843; ZN843_HUMAN; ZNF843. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 神经生物学 转录调节因子 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 37kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human ZNF843 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ZNF843 is a 348 amino acid protein that is encoded by a gene which maps to chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The ZNF843 gene product has been provisionally designated MGC46336 pending further characterization. Similarity: Contains 2 C2H2-type zinc fingers. Database links: Entrez Gene: 283933 Human SwissProt: Q8N446 Human Unigene: 722243 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
ZNF843是由一个基因编码的348氨基酸蛋白质，该基因映射到16号染色体。染色体16在大约9千万碱基对中编码900多个基因，占人类细胞DNA的近3%，并且与多种遗传病有关。GAN基因位于16号染色体上，随着突变，可能导致巨大的轴突神经病变，一种神经系统紊乱，特征是随着生长而增加功能障碍。罕见的Rubinstein-Taybi综合征也通过编码关键CREB结合蛋白的CREBBP基因与16号染色体相关。Rubinstein Taybi的症状包括精神发育迟滞和肿瘤生长和白细胞肿瘤的易感性。Crohn病是通过NOD2基因与16号染色体相关的胃肠道炎症状态。系统性红斑狼疮和许多其它与染色体16的着丝粒周区相关的自身免疫性疾病导致SLC5A11被鉴定为潜在的自身免疫调节剂。ZNF843基因产物已暂时指定为MGC46336，有待进一步鉴定。