Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Mouse Granulocyte-Macrophage Colony Stimulating Factor (Mouse GM-CSF)
                
                

                
91108ES08
                
                

                
5 μg
                
                

                
815.00
                
            
            

                

                
91108ES60
                
                

                
100 μg
                
                

                
8515.00
                
            
            

                

                
91108ES76
                
                

                
500 μg
                
                

                
22115.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) is a powerful growth and differentiation factor which acts on hematopoietic progenitor cells and also activates differentiated granulocytes and macrophages. The 22 kDa glycosylated GMCSF, similar to IL3 and IL5, is a cytokine with a core of four bundled alpha -helices. Mature human GMCSF shares 63%70% amino acid sequence identity with canine, feline, porcine, and rat GMCSF and 54% with mouse GMCSF. GM-CSF has been and is still widely used as an adjuvant in clinical trials of vaccination with autologous tumor cells, peptides and/or dendritic cells in a variety of human neoplasms. The effects of GM-CSF on HIV-1 replication in primary monocytes and macrophages, and in related cell lines, have demonstrated augmentation of HIV-1 expression in vitro.
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
Granulocyte/Macrophage Colony-Stimulating Factor, GM-CSF, CSF-2, MGI-1GM, Pluripoietin-α
                
            
            

                

                
Accession
                
                

                
P01587
                
            
            

                

                
GeneID
                
                

                
12981
                
            
            

                

                
Source
                
                

                
E.coli-derived mouse GM-CSF protein, Ala18-Lys141.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 14.1 kDa.
                
            
            

                

                
AA Sequence
                
                

                
APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK PGQK
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.