Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Human Basic Fibroblast Growth Factor (Human FGF-2)
                
                

                
91330ES10
                
                

                
10 μg
                
                

                
815.00
                
            
            

                

                
91330ES60
                
                

                
100 μg
                
                

                
2295.00
                
            
            

                

                
91330ES76
                
                

                
500 μg
                
                

                
6035.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
 
    
FGF basic, also known as FGF-2 and HBGF-2, is a member of the FGF superfamily of mitogenic proteins which show 35-60% amino acid conservation. Human FGF acidic shares 54% amino acid (aa) sequence identity with FGF basic and 17%-33% with other human FGFs. It shares 92%, 96%, 96%, and 96% aa sequence identity with bovine, mouse, porcine, and rat FGF acidic,respectively, andexhibits considerable species crossreactivity. Alternate splicing generates a truncated isoform of human FGF acidic that consistsoftheNterminal 40% ofthemolecule and functions as a receptor antagonist. The effects of androgen and FGF-2 could be partly reversed with a specific anti-FGF-2 immunoglobulin G or by suramin, which inhibits binding of FGFs to their high affinity receptors. Additionally, bFGF is frequently used for a critical component of cell culture medium, e.g., human embryonic stem cell culture medium, serum-free culture systems.
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
bFGF, FGF basic, FGF2, FGF-2, fibroblast growth factor 2 (basic), HBGF-2, Prostatropin
                
            
            

                

                
Accession
                
                

                
P09038
                
            
            

                

                
GeneID
                
                

                
2247
                
            
            

                

                
Source
                
                

                
E.coli-derived human FGF, Pro143-Ser288, with an N-terminal Met.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 16.5 kDa.
                
            
            

                

                
AA Sequence
                
                

                
MPALPEDGGS GAFPPGHFKD PKRLYCKNGG FFLRIHPDGR VDGVREKSDP HIKLQLQAEE RGVVSIKGVC ANRYLAMKED GRLLASKCVT DECFFFERLE SNNYNTYRSR KYTSWYVALK RTGQYKLGSK TGPGQKAILF LPMSAKS
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.
                
            
            

                

                
Purity
                
                

                
>96% by SDS-PAGE and HPLC analyses.
                
            
            

                

                
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