FITC标记的多发性外生骨疣样蛋白3抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的多发性外生骨疣样蛋白3抗体

FITC标记的多发性外生骨疣样蛋白3抗体

商家询价

产品名称： FITC标记的多发性外生骨疣样蛋白3抗体

英文名称： Anti-EXTL3/FITC

产品编号： HZ-13123R-FITC

产品价格： null

产品产地： 中国/上海

品牌商标： HZbscience

更新时间： 2023-08-17T10:24:20

使用范围： ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-EXTL3/FITC Conjugated antibody

FITC标记的多发性外生骨疣样蛋白3抗体

 

英文名称 Anti-EXTL3/FITC
中文名称 FITC标记的多发性外生骨疣样蛋白3抗体
别    名 botv; DKFZp686C2342; Exostoses (multiple)-like 3; Exostoses-like 3; Exostosin-like 3; EXT-related protein 1; EXTL1L; EXTL3; EXTL3_HUMAN; EXTR1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; KIAA0519; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3; REG; Reg receptor; REGR; RPR.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EXTL3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.

Function:
Probable glycosyltransferase.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the glycosyltransferase 47 family.

Database links:
UniProtKB/Swiss-Prot: O43909.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

EXTL3是EXT（遗传性多发性外皮抑素）基因家族的成员，其编码硫酸乙酰肝素（HS）生物合成中的糖基转移酶。在这个家族中，C端在线虫与脊椎动物的所有成员之间是保守的。EXTL3是一种广泛表达、发育调节的单程II型膜蛋白，定位于内质网膜。EXTL3将N-乙酰氨基葡萄糖(GlcNAc)添加到多糖-蛋白质连接区和生长中的HS链中，表明它在HS链的起始和伸长中起作用。此外，EXTL3可以作为ReG受体，通过其N-末端结合Reg。