Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Rat Leukemia Inhibitory Factor (Rat LIF)
                
                

                
92113ES08
                
                

                
5μg
                
                

                
815.00
                
            
            

                

                
92113ES60
                
                

                
100μg
                
                

                
8655.00
                
            
            

                

                
92113ES76
                
                

                
500μg
                
                

                
22795.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Leukemia inhibitory factor (LIF) is a member of Interleukin 6 family. This protein is mainly expressed in the trophectoderm of the developing embryo, with its receptor LIFR expressed throughout the inner cell mass. Mature human LIF shares 78%, 82%, 91%, 88 and 87% aa sequence identity with mouse, rat, canine, bovine, and porcine LIF, respectively. LIF is multifunctional cytokines with many similar activities. LIF is structurally and functionally related to another cytokine, Oncostatin M (OSM), that binds to the high-affinity LIF receptor but not to the low-affinity LIF receptor. While some of the actions of LIF on neurons resemble those of CNTF, LIF also has broad actions outside of the nervous system that in many cases mimic those of interleukin-6 (IL-6).  
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
CDF, DIA, Differentiation-stimulating Factor, D Factor, Emfilermin, HILDA, Melanoma-derived LPL Inhibitor, MLPLI 
                
            
            

                

                
Accession
                
                

                
P17777
                
            
            

                

                
Unigene
                
                

                
Rn.44379.
                
            
            

                

                
Source
                
                

                
E.coli-derived rat LIF, Ser23-Phe202.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 19.8 kDa.
                
            
            

                

                
AA Sequence
                
                

                
SPLPITPVNA TCAIRHPCHG NLMNQIKSQL AQLNGSANAL FISYYTAQGE PFPNNVDKLC APNMTDFPPF HANGTEKTKL VELYRMVTYL GASLTNITWD QKNLNPTAVS LQIKLNATTD VMRGLLSSVL CRLCNKYHVG HVDVPCVPDN SSKEAFQRKK LGCQLLGTYK QVISVLAQAF
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.
                
            
            

                

                
Purity
                
                

                
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