FITC标记的膀胱癌突变蛋白1抗体
产品名称： FITC标记的膀胱癌突变蛋白1抗体
英文名称： Anti-MBC1/FITC
产品编号： HZ-8084R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-MBC1/FITC Conjugated antibody
FITC标记的膀胱癌突变蛋白1抗体
| 产品编号 | bs-8084R-FITC |
| 英文名称 | Anti-MBC1/FITC |
| 中文名称 | FITC标记的膀胱癌突变蛋白1抗体 |
| 别 名 | MBC1; Mutated in bladder cancer protein 1; coiled coil domain containing 112; coiled-coil domain containing 112; MBC1; CC112_HUMAN; CCDC112; Coiled coil domain containing protein 112; Coiled-coil domain-containing protein 112; Mutated in bladder cancer 1; Mutated in bladder cancer protein 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCDC112/MBC1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: CCDC112, also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome Database links: Entrez Gene: 509840 Cow Entrez Gene: 474638 Dog Entrez Gene: 153733 Human Entrez Gene: 240261 Mouse Entrez Gene: 498858 Rat SwissProt: Q8NEF3 Human SwissProt: A0AUP1 Mouse Unigene: 436121 Human Unigene: 329416 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
CCDC112，也称为McC1（突变于膀胱癌1），是一种446氨基酸的蛋白质。编码CCDC112的基因位于5号染色体上。由于选择性剪接事件，CCDC112作为两种异构体存在。第5染色体包含约6%的人类基因组DNA，包含约1000个基因编码的1亿8100万个碱基对。它通过ECRC8基因和家族性腺瘤性息肉病通过腺瘤性息肉病（APC）肿瘤抑制基因与Coojayne综合征相关。Treacher Collins综合征也是5号染色体相关的，是由TCOF1基因内的插入或缺失引起的。5号染色体P臂缺失导致CRI—Douk综合征。在治疗相关的急性髓性白血病和骨髓增生异常综合征中普遍存在5q或5号染色体的缺失。